Sleep disorders during pregnancy

............................................................................................................... 3 List of publications .............................................................................................. 7 Abbreviations ...................................................................................................... 8 Introduction ....................................................................................................... 11 Sleep in pregnancy ........................................................................................... 11 Snoring, sleep disordered breathing and obstructive sleep apnea ................... 14 Restless Legs Syndrome .................................................................................. 16 Postpartum depression ..................................................................................... 20 Adverse outcomes of pregnancy with possible association with sleep disorders ........................................................................................................... 22 Specific background of the studies in the thesis .............................................. 23 Aims .................................................................................................................... 25 Material and methods ....................................................................................... 27 Participants ...................................................................................................... 27 Questionnaires ................................................................................................. 30 Epworth Sleepiness Scale ............................................................................ 31 Edinburgh Postnatal Depression Scale ........................................................ 32 Medical and social data ................................................................................... 32 Nocturnal respiratory recordings ..................................................................... 33 Statistics ........................................................................................................... 36 Ethical considerations ...................................................................................... 38 Results and comments ...................................................................................... 41 Participants ...................................................................................................... 41 Subjective snoring ........................................................................................... 42 Nocturnal respiratory recordings ..................................................................... 44 Restless Legs Syndrome .................................................................................. 46 Daytime sleepiness .......................................................................................... 47 Postpartum depressive symptoms.................................................................... 49